10,148 research outputs found
Development of a Fuzzy Logic Model-Less Aircraft Controller
The Modeling and Control for Agile Aircraft Development (MCAAD) group at NASA Langley Research Center(LaRC) is developing techniques for Real-Time Global Modeling (RTGM) and Robust Learning Control (RLC) for NASAās Transformational Tools and Technologies Project. This project seeks to develop a systematic approach to reduce the iterative nature of aircraft design by introducing a model-less control law and enabling inflight aerodynamic modeling and controller design. The development of the flight control system without prior knowledge of the aircraft aerodynamic model makes use of TakagiSugeno-Kang fuzzy logic inference systems for pitch and roll controllers and are tested in various simulations and wind tunnel platforms. These fuzzy logic controllers are not based on a mathematical model but rather on a rule base of generic flight control laws generated from the designerās knowledge of aircraft flight mechanics. The controller architecture uses two channels to provide absolute and incremental controller commands as needed. The absolute channel is designed to reject disturbances and decrease rise time, while the incremental channel provides tracking and reduced steady state error. To provide controllers with acceptable performance without the need for tuning, a general method for selecting input and output scaling gains for the fuzzy inference systems is proposed. A performance and robustness comparison of similarly configured Type-1 and Interval Type-2 fuzzy logic controllers is made. The fuzzy logic controllers were implemented on an aircraft model in the NASA Langley 12-Foot low speed tunnel mounted on a free-to-pitch and free-to-roll rig. The development of the controller architectures and wind tunnel results are presented
Biophysical drivers of carbon dioxide and methane fluxes in a restored tidal freshwater wetland
Wetlands store large amounts of carbon (C) in biomass and soils, playing a crucial role in offsetting greenhouse gas (GHG) emissions; however, they also account for 30% of global yearly CH4 emissions. Anthropogenic disturbance has led to the decline of natural wetlands throughout the United States, with a corresponding increase in created and restored wetlands. Studies characterizing biogeochemical processes in restored forested wetlands, particularly those that are both tidal and freshwater, are lacking but essential for informing science- based carbon management
Regioselective Reactions of Highly Substituted Arynes
The fully regioselective reactivity of four new highly substituted silyl aryl triflate aryne precursors in aryne acyl-alkylation, acyl-alkylation/condensation, and heteroannulation reactions is reported. The application of these more complex arynes provides access to diverse natural product scaffolds and obviates late-stage functionalization of aromatic rings
Provision of Fluoride Varnish Treatment by Medical and Dental Care Providers: Variation by Race/Ethnicity and Levels of Urban Influence
Objective: In 2004, Wisconsin Medicaid policy changed to allow medical care providers to be reimbursed for fluoride varnish treatment (FVT) to children\u27s teeth to improve access and utilization. To date, no study has been published on whether geographic and racial/ethnic variation in the provision of FVT in response to this policy change exists. This study\u27s objective is to examine the association of rates of FVT for children enrolled in Wisconsin Medicaid with race/ethnicity, urban influence codes (UIC), and dental health professional shortage area (DHPSA) designation based on county of residence.
Methods: A retrospective, preāpost design was used based on FVT claims for children in the Wisconsin Medicaid program from 2002 to 2006. Poisson regression models were used to evaluate the association of rates of FVT claims with race/ethnicity, UIC, and DHPSA designation.
Results: The rate of FVT claims varied by resident county-type according to UIC and DHPSA designation, age, and race/ethnicity. Post-policy, the largest increases were observed for Native Americans residing in non-DHPSA counties, enrollees living in rural counties, and for Hispanics living in partial and entire DHPSA counties. African-Americans residing in partial DHPSA and metropolitan counties displayed the lowest rates of FVT claims.
Conclusions: Overall access and utilization of FVT increased, but substantial racial/ethnic and geographic variation in the provision of FVT for children enrolled in Wisconsin Medicaid was observed. Future policies should incorporate measures that will specifically address the racial and geographic variations identified in this study
Ventricular Tachycardia in the Absence of Structural Heart Disease
In up to 10% of patients who present with ventricular tachycardia (VT), obvious structural heart disease is not identified. In such patients, causes of ventricular arrhythmia include right ventricular outflow tract (RVOT) VT, extrasystoles, idiopathic left ventricular tachycardia (ILVT), idiopathic propranolol-sensitive VT (IPVT), catecholaminergic polymorphic VT (CPVT), Brugada syndrome, and long QT syndrome (LQTS). RVOT VT, ILVT, and IPVT are referred to as idiopathic VT and generally do not have a familial basis. RVOT VT and ILVT are monomorphic, whereas IPVT may be monomorphic or polymorphic. The idiopathic VTs are classified by the ventricle of origin, the response to pharmacologic agents, catecholamine dependence, and the specific morphologic features of the arrhythmia. CPVT, Brugada syndrome, and LQTS are inherited ion channelopathies. CPVT may present as bidirectional VT, polymorphic VT, or catecholaminergic ventricular fibrillation. Syncope and sudden death in Brugada syndrome are usually due to polymorphic VT. The characteristic arrhythmia of LQTS is torsades de pointes. Overall, patients with idiopathic VT have a better prognosis than do patients with ventricular arrhythmias and structural heart disease. Initial treatment approach is pharmacologic and radiofrequency ablation is curative in most patients. However, radiofrequency ablation is not useful in the management of inherited ion channelopathies. Prognosis for patients with VT secondary to ion channelopathies is variable. High-risk patients (recurrent syncope and sudden cardiac death survivors) with inherited ion channelopathies benefit from implantable cardioverter-defibrillator placement. This paper reviews the mechanism, clinical presentation, and management of VT in the absence of structural heart disease
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Brain-Blood Partition Coefficient and Cerebral Blood Flow in Canines Using Calibrated Short TR Recovery (CaSTRR) Correction Method.
The brain-blood partition coefficient (BBPC) is necessary for quantifying cerebral blood flow (CBF) when using tracer based techniques like arterial spin labeling (ASL). A recent improvement to traditional MRI measurements of BBPC, called calibrated short TR recovery (CaSTRR), has demonstrated a significant reduction in acquisition time for BBPC maps in mice. In this study CaSTRR is applied to a cohort of healthy canines (n = 17, age = 5.0 - 8.0 years) using a protocol suited for application in humans at 3T. The imaging protocol included CaSTRR for BBPC maps, pseudo-continuous ASL for CBF maps, and high resolution anatomical images. The standard CaSTRR method of normalizing BBPC to gadolinium-doped deuterium oxide phantoms was also compared to normalization using hematocrit (Hct) as a proxy value for blood water content. The results show that CaSTRR is able to produce high quality BBPC maps with a 4 min acquisition time. The BBPC maps demonstrate significantly higher BBPC in gray matter (0.83 Ā± 0.05 mL/g) than in white matter (0.78 Ā± 0.04 mL/g, p = 0.006). Maps of CBF acquired with pCASL demonstrate a negative correlation between gray matter perfusion and age (p = 0.003). Voxel-wise correction for BBPC is also shown to improve contrast to noise ratio between gray and white matter in CBF maps. A novel aspect of the study was to show that that BBPC measurements can be calculated based on the known Hct of the blood sample placed in scanner. We found a strong correlation (R 2 = 0.81 in gray matter, R 2 = 0.59 in white matter) established between BBPC maps normalized to the doped phantoms and BBPC maps normalized using Hct. This obviates the need for doped water phantoms which simplifies both the acquisition protocol and the post-processing methods. Together this suggests that CaSTRR represents a feasible, rapid method to account for BBPC variability when quantifying CBF. As canines have been used widely for aging and Alzheimer's disease studies, the CaSTRR method established in the animals may further improve CBF measurements and advance our understanding of cerebrovascular changes in aging and neurodegeneration
Sensitivity of IceCube-DeepCore to neutralino dark matter in the MSSM-25
We analyse the sensitivity of IceCube-DeepCore to annihilation of neutralino
dark matter in the solar core, generated within a 25 parameter version of the
minimally supersymmetric standard model (MSSM-25). We explore the
25-dimensional parameter space using scanning methods based on importance
sampling and using DarkSUSY 5.0.6 to calculate observables. Our scans produced
a database of 6.02 million parameter space points with neutralino dark matter
consistent with the relic density implied by WMAP 7-year data, as well as with
accelerator searches. We performed a model exclusion analysis upon these points
using the expected capabilities of the IceCube-DeepCore Neutrino Telescope. We
show that IceCube-DeepCore will be sensitive to a number of models that are not
accessible to direct detection experiments such as SIMPLE, COUPP and XENON100,
indirect detection using Fermi-LAT observations of dwarf spheroidal galaxies,
nor to current LHC searches.Comment: 15 pages, 13 figures. V2: Additional comparisons are made to limits
from Fermi-LAT observations of dwarf spheroidal galaxies and to the 125 GeV
Higgs signal from the LHC. The spectral hardness section has been removed.
Matches version accepted for publication in JCAP. V3: Typos correcte
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